Trey Lance of the San Francisco 49ers has injured his ankle as Jimmy Garoppolo takes on the Seattle Seahawks

SANTA CLARA, Calif. — San Francisco 49ers quarterback Trey Lance left Sunday’s game against the Seattle Seahawks with 2:20 left in the first quarter with a right ankle injury and will not return.

Lance remained on the field for a few moments in obvious pain after taking a hit from Seahawks linebacker Cody Barton. His right leg was placed in an overhead cast and his teammates quickly gathered around him to offer words of encouragement before he left the pitch on a trolley and headed for the locker room.

With 2:33 to go in the opening quarter, the Niners staged a zone read game in which Lance had the option of handing it to receiver Ray-Ray McCloud or keeping it. He opted to keep it and ran to the middle where Barton met him in the hole. Lance fell awkwardly as his right leg seemed to curl under him.

Jimmy Garoppolo, the veteran quarterback Lance replaced in the offseason, came into the game and completed his first 4-yard attempt before the Niners settled for a field goal.

Lance was 2 of 3 for 30 yards and had three carries for 13 yards before he left.


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