A new DNA test developed in the United Kingdom can predict precisely if patients at high risk will develop colorectal cancer over the five years.
People with inflammatory intestine disease (MII) – which includes conditions such as ulcerative colitis and that of Crohn – are up to four times more likely to obtain this type of cancer, also called cancer of cancer The intestine.
As a preventive measurement, people with MII generally get more screening in the form of colonoscopies – but this new test is more than 90% to predict the risk of intestinal cancer before even starting.
Although colonoscopies can detect precancerous cells in the intestines, new research from the Institute of Cancer Research (CHR) in the United Kingdom has been able to predict which of these precancerous cells would turn into cancer.
They have developed a specific algorithm at more than 90% to determine if a patient would have colorectal cancer over the next five years.
The tests have been carried out with tissue samples, but they hope to be able to use their results to create a blood test that performs the same thing and can be used as a diagnostic tool in hospitals.
“Most people with ulcerative colitis or Crohn’s disease will not develop intestine cancer,” Professor Trevor Graham said in a press release.
“But for those who have these conditions and who show signs of preparing in their colon, there are decisions that are difficult to make.
“Either they watched it regularly, in the hope that it does not become cancer, or they have removed their intestine to guarantee that they do not obtain cancer in the future. None of these options is particularly pleasant.
“Our test and algorithm give people with MII and doctors who take care of them, the best possible information so that they can make the right decision on how to manage their risk of cancer.”
Dr. Iain Foulkes, our executive director of research and innovation at Cancer Research UK, hopes that the test will save time and money to people on unnecessary tests while receiving care to those who have it Need faster.
“The treatment of intestine cancer is much more likely to be effective if you catch the disease earlier,” he said.
“Having Crohn or Colitis is a risk known for intestine cancer, but the risk varies considerably between the different people, and so far, we have had to adopt a unique approach to prevent it.
“With this research, we can concentrate resources on the treatment of people with MII which are very at high risk, saving precious health services. We can also give people at a lower risk and remove the fear of intestine cancer in the future. »»
