| Player | Pos. | 2019-20 team(s) | 2020-21 team |
| 1. Alex Pietrangelo | D | Blues | Golden Knights (7 years, $61.6 million) |
| 2. Torey Krug | D | Bruins | Blues (7 years, $45.5 million) |
| 3. Taylor Hall | LW | Devils/Coyotes | Sabres (1 year, $8 million) |
| 4. Robin Lehner | G | Blackhawks/Golden Knights | Golden Knights (5 years, $25 million) |
| 5. Tyler Toffoli | W | Kings/Canucks | Canadiens (4 years, $17 million) |
| 6. Jacob Markstrom | G | Canucks | Flames (6 years, $36 million) |
| 7. TJ Brodie | D | Flames | Maple Leafs (4 years, $20 million) |
| 8. Ilya Kovalchuk | LW | Kings/Canadiens/Capitals | |
| 9. Mike Hoffman | F | Panthers | |
| 10. Tyson Barrie | D | Maple Leafs | Oilers (1 year, $3.75 million) |
| 11. Anton Khudobin | G | Stars | Stars (3 years, $10 million) |
| 12. Derek Grant | C | Ducks/Flyers | Ducks (3 years, $4.5 million) |
| 13. Jesper Fast | RW | Rangers | Hurricanes (3 years, $6 million) |
| 14. Kevin Shattenkirk | D | Lightning | Ducks (3 years, $11.7 million) |
| 15. Sami Vatanen | D | Devils/Hurricanes | |
| 16. Cam Talbot | G | Flames | Wild (3 years, $11 million) |
| 17. Mikael Granlund | C | Predators | |
| 18. Bobby Ryan* | F | Senators | Red Wings (1 year, $1 million) |
| 19. Braden Holtby | G | Capitals | Canucks (2 years, $8.6 million) |
| 20. Thomas Greiss | G | Islanders | Red Wings (2 years, $7.2 million) |
| 21. Erik Gustafsson | D | Blackhawks/Flames | Flyers: 1 year, $3 million contract |
| 22. Travis Hamonic | D | Flames | |
| 23. Chris Tanev | D | Canucks | Flames (4 years, $18 million) |
| 24. Justin Schultz | D | Penguins | Capitals (2 years, $8 million) |
| 25. Pat Maroon | LW | Lightning | Reportedly re-signed with Lightning |
| 26. Corey Crawford | G | Blackhawks | Devils (2 years, $7.8 million) |
| 27. Cody Eakin | C | Golden Knights/Jets | Sabres (2 years, $4.5 million) |
| 28. Erik Haula | LW | Hurricanes/Panthers | |
| 29. Derick Brassard | C | Islanders | |
| 30. Evgenii Dadonov | RW | Panthers | Senators (3 years, $15 million) |
| 31. Alex Galchenyuk | C | Penguins/Wild | |
| 32. Joe Thornton | C | Sharks | Maple Leafs (1 year, $700,000) |
| 33. Wayne Simmonds | RW | Devils/Sabres | Maple Leafs (1 year, $1.5 million) |
| 34. Joel Edmundson | D | Hurricanes/Canadiens | Canadiens (4 years, $14 million) |
| 35. Kyle Clifford | LW | Kings/Maple Leafs | Blues (2 years, $2 million) |
| 36. Henrik Lundqvist^ | G | Rangers | Capitals (1 year, $1.5 million) |
| 37. Josh Leivo | LW | Canucks | Flames (1 year, $875,000) |
| 38. Nate Thompson | C | Canadiens/Flyers | Jets (1 year, $750,000) |
| 39. Conor Sheary | LW | Sabres/Penguins | |
| 40. Brenden Dillon | D | Sharks/Capitals | Capitals (4 years, $15.6 million) |
| 41. Vladislav Namestnikov | C | Avalanche | Red Wings (2 years, $4 million) |
| 42. Matt Martin | LW | Islanders | |
| 43. Zdeno Chara | D | Bruins | |
| 44. Andy Greene | D | Devils/Islanders | |
| 45. Dylan DeMelo | D | Senators/Jets | Jets (4 years, $12 million) |
| 46. Mark Borowiecki | D | Senators | Predators (2 years, $4 million) |
| 47. Patrick Marleau | C | Sharks/Penguins | Sharks (1 year, $700,000) |
| 48. Zach Bogosian | D | Sabres/Lightning | Maple Leafs (1 year, $1 million) |
| 49. Mikko Koivu | C | Wild | Blue Jackets (1 year, $1.5 million) |
| 50. Jimmy Howard | G | Red Wings | |
