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Ivermectin – once touted as a Covid treatment by Tories – does not greatly improve recovery, clinical trial finds

Ivermectin, a drug once touted by Conservatives as a treatment for Covid, does not significantly improve recovery time for people with mild to moderate Covid-19, large clinical trial published in peer-reviewed journal finds of reading.

People who took ivermectin recovered from Covid in 12 days while people who didn’t take the drug recovered in 13 days, according to the study published Friday in the Journal of American Medical. Association. Ivermectin has been approved to treat parasitic worms in humans, but is primarily used as a dewormer for horses.

“Among outpatients with mild to moderate COVID-19, treatment with ivermectin, compared to placebo, did not significantly improve recovery time,” wrote the team of scientists led by Dr. Duke University School of Medicine. “These results do not support the use of ivermectin in patients with mild to moderate COVID-19,” they concluded.

Early in the pandemic, when there were few treatment options, ivermectin gained national prominence when a few conservative physician groups, including Front Line COVID-19 Critical Care Alliance and America’s Frontline Doctors, began to tout the drug on social media and elsewhere as a treatment for Covid. But there was little data to support these claims and a study by Dr. Pierre Kory, a Wisconsin critical care physician and president of the critical care alliance, claiming it was an effective treatment. , was then retracted for having erroneous data.

The latest trial involved 817 people who took ivermectin tablets for three days and compared them to 774 who received a placebo. Participants who took ivermectin received a daily dose based on their weight. Covid recovery was defined as three consecutive days without symptoms.

One person died in the ivermectin group while no one who received the placebo died. The number of people hospitalized in each group was the same at nine participants each.

The study was conducted at 93 sites in the United States from June 2021 to May 2022, when the delta variant and then the omicron variant were dominant.

The Food and Drug Administration has not approved ivermectin for the treatment or prevention of Covid and has repeatedly warned people against taking the drug for any purpose other than its approved purpose.

Public interest in ivermectin increased at the start of the pandemic when a laboratory study indicated that the drug slowed the replication of the virus that causes Covid in a petri dish. But several trials have now found that ivermectin provides no significant benefit to patients against Covid.

A New England Journal of Medicine study, published in May, found that ivermectin did not reduce the risk of hospitalization from Covid.

Ivermectin is approved in the United States in liquid or paste form to treat parasites in animals. There is also an FDA-approved tablet version to treat parasitic worms, head lice, and certain skin conditions in people.

“There’s a lot of misinformation around, and you may have heard that it’s okay to take high doses of ivermectin. It’s not okay,” the FDA says on its website, warning people that they might overdose.

The drug regulator has also sternly warned people against taking ivermectin formulations designed for animals such as horses and cows.

“On the one hand, animal drugs are often very concentrated because they are used for large animals like horses and cows, which weigh much more than us, up to a ton or more. Such high doses can be highly toxic in humans,” he added. says the FDA.


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