Intestine cancer prediction test for patients with MII 90% precise

According to research, a new method of detecting intestine cancer is more than 90% to predict higher risks developing the disease, according to research.

About 500,000 people in the United Kingdom live with inflammatory intestine disease (MII), including Crohn and ulcerative colitis.

Currently, they are offered regular controls of precancerous growths in their intestine which, if detected, indicate around 30% of the intestine cancer are developing over 10 years.

But British research revealed that DNA changes in these precancerous cells, when analyzed by an algorithm, were more than 90% to predict that would develop intestine cancer over the next five years.

Researchers have used tissue samples from MII patients – but they hope that their method can be used to develop a simple blood test to identify patients with the most at risk.

“Research like this will save lives,” said Craig Foster, of Waterlooville, whose woman, Fariba, died of intestine cancer in February 2024.

Fariba had lived with an ulcerative colitis since the age of 18, when three -quarters of his intestine were removed.

“It makes me comforting to know that there are scientists who are working at the moment so that no one will live the same situation in the same situation,” said Craig.

“Fariba died only six months after her diagnosis.

“Even if it was shortly, it was the worst moment.

“Cancer does not make prisoners – and it doesn’t matter who you are or what the minutes of life, everyone is affected in one way or another”, “

Professor Trevor Graham, of the London Cancer Research Institute, said: “Most people with ulcerative colitis or Crohn’s disease will not develop intestine cancer.

“But for those who have these conditions and who show signs of pre-cancer in their colon, there are decisions that are difficult to make.

“Either they watched it regularly, in the hope that it does not become cancer, or they have removed their intestine to guarantee that they do not obtain cancer in the future.

“None of these options is particularly pleasant.

“Our test and our algorithm give people with MII and the doctors who take care of them, the best possible information so that they can make the right decision on how to manage their risk of cancer.”

Marianne Radcliffe, of the Crohn’s & Colitis UK charitable organization, said that it was really a positive new for those who live with the conditions.

“People tell us that one of the most difficult things to live with Crohn or colitis is uncertainty – in daily and long -term life.

“As with inflammatory intestine disease, we know earlier that you will discover cancer, the better.

“Anything that allows early detection with faster and less invasive diagnostic tests, eliminating part of this uncertainty, is extremely exciting.”

Dr. Iain Foulkes, from Cancer Research UK, who financed research, says that technological advances are resuming understanding of diseases such as cancer.

“The sequencing of the genome is now much cheaper and more widespread than ever-and that changes the way we look at cancer,” he said.

“Obtaining a complete reading of tumor DNA means that we can see a much greater image of how someone’s cancer started and how it is likely to change over time.

“With this research, we can concentrate resources on the treatment of people with MII which are very at high risk, which allows health services to save time and money.

“We can also give the risks of mind at a lower risk and eliminate the fear of intestine cancer in the future.”