About one in three Australians are currently living with chronic inflammatory diseases, such as celiac disease, inflammatory intestine disease and rheumatoid arthritis.
But how this inflammation occurs and causes the disease remains largely unknown.
Dr. Cyril Seillet, a main author of the newspaper, said that the team’s conclusions were an important breakthrough that could help determine how chronic inflammation occurs at the source.
“We have shown that each meal we consume actively shapes our intestinal health,” said Dr. Seillet.
“The more we eat saturated fats, the more inflammation that accumulates – gradually weakening our intestinal defenses and increasing our sensitivity to chronic inflammation.
“But this accumulation of inflammation is initially silent, remaining hidden in our body until years later, where it can present itself as chronic inflammation.”
The researchers were able to detect microscopic changes to the health and the functioning of the intestine in mice, even after a few meals rich in fat, despite the mice not having visible symptoms of inflammation, such as weight gain.
“This shows what facility can be developed without an immediate alert,” said Dr. Seillet.
“Although meals rich in occasional fat will not enter your intestine protection barrier, a coherent diet rich in saturated fats lays the foundations for chronic intestinal inflammation to be presented in the future.”
