A recent study in the United States revealed that estrogen creams, commonly used to mitigate Menopause symptomsare not only without danger for elderly women diagnosed with breast cancerBut can also be correlated with the increase in survival rates.
Research, which was presented at the ASCO meeting, said that the survivors of postmenopausic breast cancer who used Hormonal creams has experienced a reduced risk of progression, recurrence or death of the disease. These results question the previous concerns that creams could stimulate the growth of breast cancer cells based on hormones.
Vaginal estrogen creams are frequently used to treat the symptoms of menopause such as vaginal drought, discomfort and discomfort and discomfort Pain during sexual intercourse. Following previous concerns, many breast cancer survivors avoid these treatments.
The researchers examined the files of the national database on 18,620 patients with breast cancer aged 65 and over who were diagnosed between 2010-2017, including 800 who used estrogen vaginal creams.
After taking into account the patients’ breed, the cancer stage, treatments and other factors, researchers have seen a statistically significant increase in overall survival in patients who used vaginal estrogens.
Cream users have also experienced a significant increase in specific survival for breast cancer, the diagnosis interval on the death of breast cancer.
On average, estrogen cream users had a risk of 47% death of breast cancer and a risk of death of 44% of any cause during the study period, compared to non-users.
Even in patients whose tumors were known to use hormones for growth, the use of estrogen cream was associated with a risk of death of 38% of any cause.
Main symptoms of breast cancer in women
NHS
Symptoms of breast cancer in women may include:
- a bump or swelling in your chest, chest or armpit
- a change in the skin of your breast, such as Dimpling or redness
- a change in size or shape of one or two breasts
- Mamelon discharge (if you are not pregnant or breastfed), which can be blood
- A change in the shape or appearance of your nipple, as it turns inward (inverted nipple) or an eruption on it (can look like eczema)
- Pain in your breast or armpit that does not disappear
Estrogen cream users with positive hormonal breast cancer also had a lower risk of breast cancer, but this difference was not statistically significant.
The use of creams for more than seven years seemed to confer an additional survival advantage.
“These results add to an increasing contemporary paradigm change that local hormone therapy is not associated with an increased risk for overall or specific survival for breast cancer, which has significant clinical implications,” the researchers said.
