Charlie Sheen’s ex linked to Matthew Perry death investigation: report

A criminal investigation into Matthew Perry’s death could include information from Charlie Sheen’s ex-wife, Brooke Mueller.

Mueller, 46, was reportedly questioned “multiple times” about Perry’s death in October, sources told InTouch Weekly.

Authorities reportedly tried to contact Mueller at the nursing home where she is staying, but the actress was not home when officers arrived with a search warrant last month.

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A source told the outlet that Mueller “was working out” at the time, but was “completely cooperative” when she returned.

“She has hired lawyers and had several meetings with law enforcement since they arrived at her sober home with a search warrant. She is remaining tight-lipped about the situation,” the source said.

“It’s hard to say or know exactly what her role (in Matthew’s death) is, but she’s adamant she had nothing to do with it.”

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Representatives for Mueller did not immediately respond to Fox News Digital’s request for comment.

Authorities reportedly seized an iPhone and laptop from Mueller. Their relationship is still unclear, but a source said Mueller met the late “Friends” star “in rehab,” where they “formed an unexpected friendship.”

Mueller and Sheen were married for three years before divorcing in 2011. A judge recently granted Sheen full custody of their twins if Mueller failed a drug or alcohol test. The two share joint custody, though the twins live primarily with Sheen.

Los Angeles Police Department Officials confirmed to Fox News Digital that the department is still actively working on the criminal investigation into Perry’s death.

“The department has an open and ongoing investigation into the death of Matthew Perry,” authorities said.

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The “Fools Rush In” actor died Oct. 28 after apparently drowning in a hot tub at his home in the Pacific Palisades neighborhood of Los Angeles. He was 54.

Last month, Los Angeles Police Capt. Scot Williams said in an email that the department was working with the DEA and the U.S. Postal Inspection Service to determine why Perry had so much ketamine in his system when he died in October, the Associated Press reported.

When Fox News Digital asked about the status of the investigation, the U.S. Attorney’s Office declined to comment.

Traces of ketamine were detected in Perry’s stomach contents, according to his autopsy, which stated his death was due to the “acute effects of ketamine.”

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“The exact method of drug absorption in Mr. Perry’s case is unknown,” the report states. Other factors contributed to his death, including “coronary artery disease and the effects of buprenorphine,” the report said. “Prescription medications and loose pills” were also found in his home, according to the autopsy.

Ketamine is a dissociative anesthetic drug with “established medical and surgical uses,” the autopsy detailed. Perry reportedly received “ketamine infusion therapy for depression and anxiety.”

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His last known treatment was more than a week before his death, but the medical examiner determined that “the ketamine present in his system at the time of death could not have come from this infusion therapy, since the half-life of ketamine is 3 to 4 hours, or less.”